What is longevity medicine? How to live more years in better health

Why I'm telling you this
Longevity medicine is not simply about living more years. It is about trying to live those years with better health, autonomy, energy, and quality of life.
Quick answer
What is longevity medicine?
Longevity medicine is a medical approach that integrates prevention, individualized risk assessment, health monitoring, and knowledge of the biological processes of aging. Its goal is to preserve physical, metabolic, cognitive, and functional capacity for as long as possible — in other words, to increase the years lived in good health (healthspan). It does not promise eternal life or rejuvenation: it is grounded in prevention, medical evaluation, and decisions supported by scientific evidence.
"Doctor, what exactly is longevity medicine?"
There is a question my patients ask me more and more frequently:
"Doctor, I have heard about longevity medicine, but I don't really understand what it is. Is it about rejuvenating? About living to 100? About taking vitamins? About having special tests done?"
The question is perfectly understandable.
In recent years, the concept of longevity has become enormously popular.
People talk about biological age, cellular rejuvenation, supplements, hormones, fasting, the microbiome, artificial intelligence, and treatments aimed at slowing ageing.
But within all this information there is a mixture of solid scientific knowledge, promising research, and commercial claims that have yet to be proven.
That is why I consider it important to explain what longevity medicine really means.
I am Dr. Florian Vallecillo Cabrera, a physician dedicated to longevity medicine, metabolic health, and disease prevention.
In my clinical practice, I am especially interested in understanding how we can preserve a person's health over the years, identify modifiable risk factors, and act before avoidable complications arise.
Because there is a fundamental difference between living many years and living many years in good health.
And that is precisely where longevity medicine begins.
1. What is longevity medicine?
Longevity medicine is a medical approach that integrates prevention, individualised risk assessment, health monitoring, and knowledge of the biological processes of ageing.
Its primary goal is to preserve, for as long as possible, a person's physical, metabolic, cognitive, and functional capacity.
It does not aim to replace conventional medicine.
On the contrary, it uses its most effective tools and combines them with a preventive and longitudinal vision.
It is particularly interested in one question:
What can we do today to reduce the risk of disease, disability, and loss of autonomy ten, twenty, or thirty years from now?
Longevity medicine draws on knowledge from various disciplines, including preventive medicine, internal medicine, clinical nutrition, endocrinology, cardiology, exercise physiology, geriatrics, and aging research.
It is not a single technique or a specific treatment.
It is a way of approaching long-term health.
2. The difference between lifespan and healthspan
In longevity medicine, we frequently use two English terms.
Lifespan: how long we live
Lifespan means total duration of life.
It is the number of years that pass between birth and death.
Healthspan: how long we live in good health
Healthspan refers, broadly speaking, to the period of life during which we maintain satisfactory health and functional capacity.
Although there is not yet a universal scientific definition or a single way of measuring it, the concept is fundamental.
Let us imagine two people who live to the age of 90.
The first develops significant physical limitations at 65 and spends the following decades with very reduced autonomy.
The second maintains a good capacity to walk, carry out daily activities, participate socially, and make decisions until much more advanced ages.
Both have the same lifespan.
But their experience of health and autonomy is very different.
3. What does ageing healthily mean?
The World Health Organization defines healthy ageing in terms of the development and maintenance of the functional capacity that enables well-being at advanced ages.
This capacity encompasses far more than the absence of disease.
It means being able to:
• Move around and maintain mobility.
• Carry out daily activities.
• Think, learn, and make decisions.
• Maintain personal relationships.
• Participate in society.
• Preserve as much independence as possible.
A person may have hypertension or diabetes and still maintain a good quality of life if their conditions are adequately managed.
For this reason, healthy longevity does not demand an impossible biological perfection.
It seeks to preserve functions and reduce risks.
4. Why do we age?
Aging is a complex biological process.
Over time, changes occur across multiple systems in the body.
Among the mechanisms that have been studied, we find:
4.1. DNA damage and repair
Our cells are continuously exposed to processes that can alter genetic material.
The body has repair systems, but their functioning and efficacy can change with age.
4.2. Epigenetic changes
Epigenetics studies mechanisms that regulate gene expression without necessarily modifying the DNA sequence.
Some epigenetic patterns change with aging.
These changes are the subject of research aimed at better understanding biological age.
4.3. Mitochondrial dysfunction
Mitochondria are involved in the production and regulation of cellular energy.
Their functioning can be altered with age and in various diseases.
However, not every symptom of fatigue means that a person has a mitochondrial disease.
Can we preserve the energy of our cells through nutrition?
4.4. Cellular senescence
Some cells enter states of senescence, characterized by changes in their activity and proliferative capacity.
Certain senescent cells can contribute to inflammatory signaling.
Eliminating or modifying these cells is an area of research, but it does not yet constitute a validated routine anti-aging treatment for healthy individuals.
4.5. Alterations in nutrient regulation
The pathways related to insulin, IGF-1, AMPK, and mTOR are involved in processes of growth, metabolism, and cellular adaptation.
They are being investigated for their relationship with aging.
However, these mechanisms are complex and do not justify using medications without medical indication.
4.6. Low-grade chronic inflammation
With age, changes in immune regulation and an increase in certain inflammatory markers may appear.
This phenomenon is studied under the concept of inflammaging.
Chronic inflammation may also be related to obesity, smoking, inflammatory diseases, and other factors.
There is no single test that can diagnose inflammatory aging in isolation.
Chronic inflammation: when what happens inside the body is reflected in the skin
4.7. Alterations in inter-organ communication
The nervous system, the endocrine system, the immune system, and metabolism interact constantly.
Changes in these interactions can influence health throughout life.
Research into these mechanisms constitutes an important part of geroscience.
5. What is geroscience?
Geroscience is the scientific field that studies how the biological mechanisms of aging contribute to the development of age-related diseases.
Its central hypothesis is that certain shared biological processes could simultaneously influence several diseases.
For example, aging constitutes an important risk factor for cardiovascular disease, type 2 diabetes, cancer, neurodegenerative disorders, and loss of functional capacity.
Geroscience attempts to understand these mechanisms and to study possible interventions.
Longevity medicine seeks to translate scientifically validated knowledge into the care of individuals.
But a clear distinction must be made between research and clinical practice.
6. How does it differ from traditional medicine?
Conventional medicine already includes prevention, early detection, and health promotion.
It would therefore be incorrect to claim that traditional medicine only treats diseases once they appear.
The difference with longevity medicine lies mainly in the integration of multiple areas of health and in the pursuit of long-term functional goals.
For example, a person may still have normal blood glucose, yet present with progressive increases in visceral fat, loss of muscle strength, elevated blood pressure, and poor sleep habits.
Each element deserves a specific assessment.
Longevity medicine attempts to integrate this data into a coherent plan, avoiding both the underestimation of risks and the excess of tests and treatments.
The goal is not to medicalize every healthy person.
The goal is to offer proportionate, evidence-based prevention.
7. What areas does longevity medicine encompass?
7.1. Cardiovascular health
Cardiovascular disease is one of the leading causes of illness and mortality.
A preventive evaluation may consider:
• Blood pressure.
• Lipid profile.
• Overall cardiovascular risk.
• Smoking.
• Diabetes.
• Family history.
• Physical activity.
• Other relevant risk factors.
In certain patients, additional tools may be used, such as measurement of lipoprotein(a), apolipoprotein B, or subclinical atherosclerosis studies when indicated.
Not all of these tests are necessary for every person.
The goal is to reduce cardiovascular risk through interventions with proven efficacy.
I had a heart attack or a stroke and my cholesterol was normal: how is that possible?
7.2. Metabolic health
Metabolic medicine occupies an important place in longevity.
Factors studied include:
• Glucose.
• Glycated hemoglobin.
• Insulin resistance when there is an indication to evaluate it.
• Obesity and body fat distribution.
• Metabolic syndrome.
• Dyslipidemia.
• Metabolic dysfunction-associated steatotic liver disease.
We must not confuse an isolated laboratory value with overall metabolic health.
Interpretation must take the clinical context into account.
Five markers that can alert us to the risk of diabetes before glucose levels rise
7.3. Clinical nutrition
Diet influences numerous health-related factors.
A nutritional assessment can examine:
• Diet quality.
• Protein intake.
• Fiber consumption.
• Macronutrient distribution.
• Energy requirements.
• Nutritional deficiencies.
• The relationship between diet and metabolic diseases.
There is no universal longevity diet.
The needs of a 35-year-old who plays sport may be different from those of a 75-year-old with sarcopenia.
Metabolic and nutritional assessment at Clínica Valorian
7.4. Muscle mass and sarcopenia prevention
The progressive loss of muscle mass and function can compromise mobility, balance and independence.
That is why longevity medicine should not focus exclusively on weight.
It must also pay attention to strength and physical capacity.
Resistance training, physical activity, and proper nutrition are fundamental tools.
Weight and body composition: why the scale does not tell you whether you have gained fat
7.5. Bone Health
The prevention of osteoporosis and fractures is part of maintaining autonomy.
Depending on age and risk factors, it may be appropriate to assess:
• History of fractures.
• Risk of falls.
• Nutritional status.
• Medications.
• Bone mineral density by densitometry when indicated.
The goal is not solely to improve a laboratory result, but to reduce fractures and disability.
7.6. Sleep and Recovery
Getting adequate sleep is essential for health.
The assessment may include sleep duration, regularity, insomnia, daytime sleepiness, and suspicion of obstructive sleep apnea.
It is not enough to wear a device that measures sleep.
Data must be interpreted clinically.
7.7. Cognitive Health
Preserving cognitive function is an important goal.
Prevention includes the control of vascular risk factors, physical activity, hearing health, sleep, and other modifiable factors.
The appearance of memory problems must be evaluated clinically and not automatically attributed to age.
7.8. Hormonal Health
Hormones change throughout life.
Menopause, hypogonadism, and certain endocrine disorders can affect health and well-being.
However, there is no justification for administering hormones to all individuals with the goal of rejuvenation.
Hormone therapy must be based on clinical indications, expected benefits, risks, and contraindications.
Optimizing hormonal health does not mean raising all hormone levels to values typical of a young person.
7.9. Immune Health and Vaccination
Infection prevention is part of healthy longevity.
Vaccines recommended based on age, medical history, and risk factors can prevent significant illnesses and complications.
Habits and conditions that affect immune function should also be reviewed.
7.10. Cancer Prevention
Rigorous longevity medicine must include oncological prevention.
This involves reducing risk factors and participating in appropriate screening programs.
Relevant measures include avoiding tobacco, limiting alcohol, maintaining physical activity, preventing certain infections, and undergoing recommended screenings.
Detection programs should be tailored to age, sex, family history, and clinical recommendations.
This does not mean systematically performing whole-body MRI scans or tumor marker panels on healthy individuals.
7.11. Mental Health and Social Relationships
Health is not limited to biological parameters.
Psychological well-being, social relationships, life purpose, and living conditions all influence functional capacity.
Prevention must also address these dimensions.
7.12. Skin Health
The skin reflects certain aging processes, but on its own it does not allow us to measure the biological age of the organism.
Sun protection, skin cancer prevention, and the treatment of dermatological conditions are all part of comprehensive care.
Aesthetic medicine can improve certain aspects of appearance, but it should not be confused with a proven intervention for extending life.
8. At What Age Should We Start?
There is no single age.
Prevention begins long before old age.
At 30 or 40 years of age, it can be important to identify risk factors, consolidate healthy habits, and prevent the development of diseases.
At 50 or 60, cardiovascular risk, metabolic health, muscle mass, menopause, bone health, and screenings may become increasingly relevant.
At 70 or 80, functional capacity, fall prevention, strength, autonomy, and medication review take on particular importance.
Longevity medicine is not reserved for older people, nor exclusively for patients with significant financial resources.
Many of its most important measures are accessible and form part of standard medical prevention.
9. What does a first longevity medicine consultation look like?
A consultation begins with a detailed medical history.
It is important to understand previous illnesses, family history, medications, diet, physical activity, sleep, habits, and personal goals.
Afterwards, a patient-tailored assessment is carried out.
It may include:
• Physical examination.
• Blood pressure.
• Body composition assessment when it provides useful information.
• Cardiovascular risk review.
• Nutritional assessment.
• Assessment of strength and physical function.
• Sleep review.
• Evaluation of metabolic factors.
• Review of screenings and vaccination.
There is no universal panel of tests that should be performed on every person.
The plan depends on the clinical findings.
Longevity medicine consultation at Clínica Valorian, Marbella
10. What tests are performed?
Tests should be selected according to age, medical history, symptoms and risk factors.
In certain patients, the following may be indicated:
• Complete blood count.
• Glucose and glycated haemoglobin.
• Lipid profile.
• Kidney function.
• Liver function.
• Specific thyroid tests.
• Assessment of iron or vitamin B12 deficiency.
• Vitamin D when there is a clinical indication.
• Other tests based on personal history and physical examination.
Not all of these tests are necessary in asymptomatic individuals.
And a broader laboratory panel does not guarantee better prevention.
11. What is biological age?
Chronological age corresponds to the number of years a person has lived.
Biological age attempts to describe characteristics of the body related to ageing.
Various estimation methods have been developed using:
• Blood biomarkers.
• DNA methylation patterns.
• Physiological variables.
• Physical function.
• Statistical models and algorithms.
Some systems are known as epigenetic clocks.
They are interesting research tools.
However, different methods can provide different estimates.
There is still no universally accepted test that precisely determines a person's true biological age or that can independently guide clinical treatment decisions.
A reduction in the age estimated by an algorithm does not necessarily demonstrate a reduction in the risk of death or disease.
Can a genetic study of methylation tell us which vitamins we need?
12. What role do smartwatches and health devices play?
Devices can record information on:
• Physical activity.
• Heart rate.
• Estimated sleep.
• Heart rate variability.
• Other physiological parameters.
They can help observe trends and support habit changes.
But their measurements have limitations.
They do not replace medical evaluation and should not be used to diagnose diseases without proper validation.
The goal is to use technology when it adds value, not to turn every daily variation into a medical problem.
13. Does longevity medicine use supplements?
Supplements may be used when there is a reasonable nutritional or clinical indication.
For example, certain deficiencies require correction.
However, it is important to distinguish between correcting a deficiency and administering supplements with the promise of slowing aging.
There is insufficient evidence to claim that a general combination of vitamins, antioxidants, or commercial products prolongs the lives of healthy people.
Some supplements can cause adverse effects or interact with medications.
More does not necessarily mean better.
14. What do we know about NAD+, NMN, and NR?
NAD+ is involved in numerous cellular metabolic reactions.
Its relationship with aging is the subject of ongoing research.
Nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) are being studied as precursors of NAD+.
Some trials have observed changes in biomarkers related to NAD+.
However, it has not been demonstrated that these supplements extend human lifespan or that they generally prevent age-related diseases.
Their clinical efficacy, long-term safety, and regulatory status must be carefully evaluated.
15. What about metformin?
Metformin is a medication widely used for type 2 diabetes and certain clinical indications.
It is being investigated for its possible effects on mechanisms related to aging.
But the results of observational studies do not demonstrate that it should be administered to healthy individuals to extend life.
Metformin can produce adverse effects and has contraindications.
It should not be used as a routine anti-aging treatment without a justified clinical indication.
16. What about rapamycin?
Rapamycin and other mTOR inhibitors have shown interesting results in experimental aging studies, especially in animals.
However, extrapolation to humans is complex.
Rapamycin has immunological and metabolic effects and can produce significant adverse reactions.
It has not been established that its use in healthy individuals prolongs life or globally improves healthy longevity.
Therefore, it should not be presented as a preventive treatment for routine use.
17. What are senolytics?
Senolytics are experimental interventions designed to act on certain senescent cells.
They represent a relevant line of research.
But the results obtained in animals do not allow us to conclude that they are effective and safe for prolonging the lives of healthy individuals.
Their widespread clinical application would be premature.
18. Does intermittent fasting work?
Intermittent fasting encompasses different eating patterns.
In certain individuals it can help reduce energy intake, improve weight control, or improve certain metabolic parameters.
But its effects depend on context.
There is no conclusive evidence that intermittent fasting extends human life more than other sustainable healthy strategies.
Furthermore, it is not appropriate for all patients.
It must be individualized, especially in people with diabetes treated with medications that can cause hypoglycemia, a history of eating disorders, frailty, or special nutritional needs.
Longevity does not consist of fasting for the greatest possible number of hours.
19. What about caloric restriction?
Caloric restriction has shown effects on longevity in various animal models.
In humans, metabolic changes and other health indicators have been studied.
However, it has not yet been demonstrated that any specific caloric restriction prolongs human survival.
Furthermore, excessive energy reduction can promote loss of muscle mass, nutritional deficiencies, and other problems.
The goal should be to maintain an adequate nutritional status.
20. Physical exercise: one of the most important tools
If I had to highlight one intervention with broad and well-established health benefits, physical exercise would be among the first I would mention.
Regular physical activity contributes to:
• Improve cardiovascular health.
• Reduce the risk of type 2 diabetes.
• Preserve functional capacity.
• Improve muscle strength.
• Maintain bone health.
• Promote psychological well-being.
• Reduce certain disease risks.
A balanced strategy typically combines aerobic activity, strength training, and balance and mobility exercises when indicated.
Intensity should be adapted to the clinical situation.
It is not necessary to practice extreme sport to obtain benefits.
Overweight? Don't simply do more exercise: distribute it better.
21. Muscle strength as a health indicator
Strength is important for carrying out daily activities and maintaining independence.
In certain populations, measures such as handgrip strength or gait speed can provide prognostic information.
But they should not be interpreted in isolation.
Prevention of functional decline includes exercise, nutrition, and treatment of associated conditions.
It is not enough to live more years: we must try to preserve the ability to make use of them.
22. The importance of sleep
Sleep plays a role in recovery processes, metabolic regulation, and cognitive function.
Poor sleep quality can be associated with multiple health problems.
Longevity medicine should identify treatable disorders, such as insomnia or obstructive sleep apnea.
It is not about chasing a perfect score on a smartwatch.
It is about achieving adequate, functional rest.
23. What place does hormonal health occupy?
Hormonal transitions are part of life.
In certain patients, the evaluation and treatment of endocrine disorders can improve symptoms and prevent complications.
For example, menopausal hormone therapy may be appropriate in selected women for recognized indications, after weighing benefits and risks.
But it should not be prescribed universally to prevent aging.
The same applies to testosterone.
Administering testosterone without a diagnosis of hypogonadism and without a clinical indication does not constitute a proven longevity strategy.
24. Is aesthetic medicine part of longevity?
Aesthetic medicine can contribute to well-being and satisfaction with appearance in certain patients.
However, we must distinguish between two objectives.
One is to improve certain visible changes in the skin or face.
The other is to preserve cardiovascular, metabolic, muscular, cognitive and functional health.
A person may look younger and still present significant risk factors.
And another may show natural signs of ageing and maintain an excellent physical capacity.
A youthful appearance does not necessarily equate to greater biological longevity.
25. What is personalised longevity medicine?
It means tailoring decisions to each person's actual situation.
Not all patients need the same tests, treatments or recommendations.
For example:
Patient A: 35 years old
They have a family history of early cardiovascular disease, smoke and present elevated cholesterol levels.
The priority may be to reduce their cardiovascular risk and address tobacco use.
Patient B: 52 years old
They present increased abdominal fat, hypertension and glycaemic alterations.
The priority may be a structured cardiometabolic intervention.
Patient C: 68 years old
They have loss of muscle strength, a history of falls, and low physical activity.
The priority may be to preserve their functional capacity and reduce the risk of fractures.
All three patients may benefit from a longevity-focused approach.
But their needs are different.
26. How is a longevity plan built?
The process can be organized into five stages.
First stage: getting to know the patient
Medical history, background, habits, medication, goals, and preferences.
Second stage: identifying risks
Assessment of cardiovascular, metabolic, nutritional, functional, and other factors as appropriate to each case.
Third stage: establishing priorities
Not all abnormalities require immediate intervention.
Priority should be given to those measures with the greatest expected clinical benefit.
Fourth stage: applying interventions
These may include lifestyle changes, indicated medical treatments, vaccination, screenings, and follow-up.
Fifth stage: evaluating results
Relevant parameters, symptoms, functional capacity, and adherence are reviewed.
The goal is not to produce increasingly complex reports.
It is to achieve results that are meaningful to the patient's health.
27. What are the results that truly matter?
Longevity medicine must value clinically relevant outcomes.
Among them:
• Reduction of cardiovascular events.
• Better control of metabolic diseases.
• Fracture prevention.
• Preservation of strength and mobility.
• Reduction of disability.
• Appropriate detection of diseases.
• Maintenance of autonomy.
• Better quality of life.
• Reduction of mortality when the intervention demonstrates it.
An improvement in an experimental biomarker may be interesting.
But it should not be automatically confused with a demonstrated improvement in these outcomes.
28. Can longevity medicine guarantee living to 100 years?
No.
No physician can guarantee a specific age of survival.
Longevity depends on multiple factors, including genetics, environment, diseases, social circumstances, and unforeseeable events.
Medicine can reduce certain risks and improve the chances of maintaining good health.
But it does not control every aspect of life.
Promises of guaranteed rejuvenation or radical life extension should be interpreted with caution.
29. Why is it important to distinguish between science and marketing?
The growing interest in longevity has generated a market of tests, supplements, programs, and treatments.
Some services incorporate useful preventive measures.
Others market costly procedures without sufficient evidence of clinical benefit.
Before recommending an intervention, we must ask ourselves:
• What problem does it aim to solve?
• Are there studies in humans?
• Have relevant clinical benefits been demonstrated?
• What are the risks?
• Is it indicated for this person?
• Is there a better-studied alternative?
Personalized nutrition based on your microbiome: science or marketing?
30. What can longevity medicine offer a healthy person?
A person who feels well may still have risk factors that are not yet symptomatic.
For example, high blood pressure, lipid abnormalities, or a family cardiovascular predisposition.
Prevention makes it possible to identify some of these risks and act in a proportionate manner.
But it is also important to avoid overdiagnosis.
A healthy person does not need to undergo tests constantly without a specific indication.
Balancing benefit and risk is part of good medicine.
31. What can it offer a person with chronic diseases?
Healthy longevity is also relevant for people who already have established conditions.
It does not mean demanding a complete absence of diagnoses.
It consists of adequately managing diseases, preventing complications, and preserving functionality.
A person with diabetes or hypertension can benefit enormously from a well-adjusted treatment plan and appropriate follow-up.
32. The importance of medical continuity
The benefits of prevention are built up over time.
A single consultation can identify important problems.
But follow-up allows us to evaluate progress and adapt decisions.
Longevity medicine should not be reduced to an annual check-up packed with tests.
It should foster a continuous, proportionate, and patient-centered clinical relationship.
33. Frequently asked questions about longevity medicine
What exactly is longevity medicine?
It is a medical approach that integrates prevention, risk assessment, monitoring and knowledge about aging in order to preserve health and functional capacity for more years.
Is it the same as anti-aging medicine?
Not necessarily. Evidence-based longevity medicine prioritizes clinical and functional outcomes, not promises of rejuvenation.
Is it an officially recognized medical specialty?
Longevity medicine is an emerging and interdisciplinary clinical field, not a medical specialty officially recognized as independent in Spain.
Is it only for older people?
No. Prevention can begin in young adulthood and be tailored to each stage of life.
What is healthspan?
It is the period of life lived with a satisfactory level of health and functional capacity. There is no universal operational definition.
What is biological age?
It is an estimate of aging-related characteristics obtained through different biomarkers or models. It is not equivalent to an exact prediction of longevity.
Do I need a genetic test?
Not necessarily. Genetic tests are indicated when there is a clinical justification and must be interpreted with appropriate counseling.
Do I need very comprehensive blood tests?
No. Tests should be selected based on medical history, age, symptoms, and risk factors.
Do longevity supplements work?
Some supplements are useful for correcting deficiencies. It has not been proven that supplements marketed for rejuvenation generally extend human lifespan.
Does NMN extend lifespan?
It has not currently been proven to extend human survival.
Does metformin slow aging?
It is an area of ongoing research, but there is insufficient evidence to routinely prescribe it to healthy individuals for that purpose.
Does rapamycin allow people to live longer?
It has shown interesting results in animals, but it has not been proven to extend the lives of healthy people and may produce adverse effects.
Is intermittent fasting mandatory?
No. It can be useful in certain circumstances, but it is neither necessary nor appropriate for everyone.
What is more important: nutrition or exercise?
Both are important and complementary. The priority depends on the clinical situation.
Does longevity medicine include cancer prevention?
Yes. It includes reduction of risk factors and screenings based on clinical recommendations.
Does hormone therapy rejuvenate?
There is no justification for using hormones indiscriminately as an anti-aging treatment. They should be used according to recognized medical indications.
Can longevity medicine help me have more energy?
It can identify and address treatable causes of fatigue, sleep problems, nutritional imbalances, or illness. It cannot guarantee an increase in energy in all patients.
How long does a longevity program last?
There is no universal duration. It is a prevention and follow-up approach tailored to each person's goals and needs.
Does longevity medicine replace my regular doctor?
No. It should complement and be coordinated with regular medical care and the relevant specialties.
Can I live to 100 thanks to longevity medicine?
There are no guarantees. Its goal is to reduce modifiable risks and preserve health — not to promise a specific age.
34. My vision of longevity medicine
As a physician, I believe that one of the great challenges of our time is not simply to increase life expectancy.
It is to prevent those additional years from being accompanied by a premature loss of health and autonomy.
I am particularly interested in the relationship between metabolism, nutrition, inflammation, body composition, physical activity, and chronic disease.
These fields are deeply interconnected.
But I also consider it essential to maintain a critical mindset.
Not everything new is necessarily better.
Not every costly technology delivers real benefits.
And not every promising mechanism discovered in a laboratory becomes a useful treatment for patients.
Longevity medicine must be rigorous, individualized, and humane.
It must listen to the patient and help them establish priorities.
We should not be chasing eternal youth.
We should strive to preserve health and the ability to enjoy life for as long as possible.
Conclusion: it is not simply about adding years to life
When people ask me what longevity medicine is, I usually sum it up in one simple idea.
Being able to walk, travel, play sport, think clearly, spend time with family, maintain relationships and preserve independence.
Those are goals that carry real meaning.
Longevity medicine combines prevention, scientific knowledge, individualised assessment and follow-up.
It does not promise immortality.
It does not eliminate all risks.
And it cannot stop aging entirely.
But it can help us make decisions that protect our health throughout life.
Because the true goal of longevity is not simply to reach old age. It is to reach it while preserving, as much as possible, the capacity to live fully.
Dr. Florian Vallecillo Cabrera · Physician dedicated to longevity medicine and healthy ageing · The Doctor Explains — Clínica Valorian, Marbella
What to remember
- —Longevity medicine seeks to increase the years lived in good health (healthspan), not just the total duration of life (lifespan).
- —It integrates cardiovascular health, metabolism, nutrition, exercise, sleep, bone, cognitive, and hormonal health into an individualized plan with ongoing follow-up.
- —There is no universal battery of tests: the assessments are chosen based on age, medical history, symptoms, and risk factors.
- —NMN, metformin, rapamycin, and senolytics remain under investigation: it has not been proven that they extend the lives of healthy people.
- —Physical exercise, muscle strength, sleep, and the control of risk factors are among the best-established tools.
Scientific references
- Organización Mundial de la Salud. Healthy ageing and functional ability. Definición de envejecimiento saludable, capacidad intrínseca y capacidad funcional. · OMS
- Balardy L, Adnot S, Gallix B, et al. Rapport 25-14. Approche clinique de la longévité en bonne santé. Bulletin de l'Académie Nationale de Médecine, 2026;210(3):202–210. · DOI
- Kroemer G, Maier AB, Cuervo AM, et al. From geroscience to precision geromedicine: Understanding and managing aging. Cell, 2025;188(8):2043–2062. · DOI
- Thor D, Barzilai D, Lyu YX, et al. From sick care to healthspan: educating the longevity physician for health maintenance and health promotion. Biogerontology, 2025;27(1). · DOI
- Masfiah S, Kurnialandi A, Meij JJ, et al. Definitions of healthspan: A systematic review. Ageing Research Reviews, 2025;111:102806. · DOI
- American Heart Association. Life's Essential 8. Ocho componentes fundamentales de la salud cardiovascular. · AHA
- National Institute on Aging. Live Long in Good Health: Could Calorie Restriction Mimetics Hold the Key? Investigación sobre metformina, rapamicina y otros compuestos, con sus limitaciones. · NIA
- Joshi M, Singh S, Rowley N, et al. Science of longevity medicine. BMJ, 2025;391:r2536. · DOI
Would you like to find out how a longevity medicine approach can help you? At Clínica Valorian, Marbella, individualized medical assessment makes it possible to review risk factors, lifestyle habits, metabolic health, and prevention goals. The aim is to develop recommendations tailored to each person, based on medical criteria and scientific evidence.
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Doctor Florian A. Vallecillo Cabrera
The doctor explains
Informational content, written and reviewed by Doctor Florian A. Vallecillo Cabrera. It does not replace an in-person consultation or an individual diagnosis.

