Clínica Valorian

Scientific News

Scientific news: study analyses, medical updates, international recommendations and innovations, with clear, evidence-based reading.

Basal cell carcinoma: a therapeutic virus could ease the treatment of the most difficult forms

Featured

Skin health & medicine

Basal cell carcinoma: a therapeutic virus could ease the treatment of the most difficult forms

A phase II trial (MedUni Vienna, Nature Cancer) tested the oncolytic virus T-VEC as a neoadjuvant in 18 patients with locally advanced basal cell carcinomas. All tumours regressed, 55.6% with a significant response, one third with no detectable tumour cells, and simplified surgery in nearly half of cases. Promising results to be confirmed in phase III; surgery remains the reference.

4 min read

Why Do We Get Wrinkles? A 'Skin-on-a-Plate' Model to Study How They Form

Featured

Skin health & medicine

Why Do We Get Wrinkles? A 'Skin-on-a-Plate' Model to Study How They Form

Published in Nature Communications, this device reproduces 'wrinkles in a Petri dish' using epithelial cells on a collagen hydrogel. It allows researchers to see how mechanical compression and dehydration create folds, and confirms the protective role of collagen, without animal experimentation. We analyse what this advance contributes — and what it does not.

Doctor Florian A. Vallecillo Cabrera· September 16, 2026· 4 min read

Practical guide to alopecia areata treatments and how severity influences choices

New

Scientific News

Practical guide to alopecia areata treatments and how severity influences choices

Alopecia areata treatment should be tailored to extent, site, progression, age, relapse pattern, and quality-of-life impact. Local therapies are often used for limited disease, while moderate-to-severe or rapidly progressive cases may warrant systemic options, including JAK inhibitors in selected patients. Recent literature adds real-world data on efficacy, safety, laboratory monitoring, pediatric use, and the supportive role of cranial prostheses.

September 16, 2026

Scientific article: potential of personalized cosmetics with bioactive ferments and copper peptides

New

Scientific News

Scientific article: potential of personalized cosmetics with bioactive ferments and copper peptides

The combination of bioactive ferments and GHK-Cu is promising in personalized cosmetics, but its value depends on barrier status, skin of color considerations, light exposure, exposome burden, and neurocutaneous reactivity.

September 16, 2026

Stress-related hair loss: scalp TGF-β/BMP pathways and the emerging role of topical nutraceutical-peptide combinations

New

Scientific News

Stress-related hair loss: scalp TGF-β/BMP pathways and the emerging role of topical nutraceutical-peptide combinations

Stress can trigger telogen effluvium or worsen other hair disorders, but not every diffuse shed is “from stress.” Scalp TGF-β/BMP signaling offers an interesting biologic framework, and a 2026 topical EGCG-biotin-Pal-GHK formulation showed mechanistic effects. Still, current evidence does not by itself establish broadly generalizable clinical efficacy or replace careful differential diagnosis.

September 16, 2026

New

Scientific News

Stress-related hair loss: scalp TGF-β/BMP pathways and the emerging role of topical nutraceutical-peptide combinations

Hair shedding linked to stress is often described as telogen effluvium, but stress may also unmask or worsen female pattern hair loss or coexist with alopecia areata. A 2026 study of topical EGCG, biotin, and Pal-GHK suggests modulation of scalp TGF-β/BMP signaling in stress-induced alopecia, offering biologic plausibility but not yet broad clinical proof [1].

September 16, 2026

New

Scientific News

Stress-related hair loss: scalp TGF-β/BMP pathways and the emerging role of topical nutraceutical-peptide combinations

Hair shedding linked to stress is often a telogen effluvium, but stress can also unmask or worsen other alopecias. A recent study of EGCG, biotin, and Pal-GHK suggests modulation of scalp TGF-β/BMP signaling, with stronger mechanistic than practice-changing clinical implications so far [1].

September 16, 2026

New

Scientific News

Stress-related hair loss: scalp TGF-β/BMP pathways and the emerging role of topical nutraceutical-peptide combinations

Hair shedding linked to stress is often described clinically as diffuse telogen effluvium, but it is frequently multifactorial. Newer evidence suggests that the scalp microenvironment and TGF-β/BMP signaling may contribute, although mechanistic findings alone do not prove broad clinical efficacy of novel topical combinations.

September 16, 2026

New

Scientific News

Stress-related hair loss: scalp TGF-β/BMP pathways and the emerging role of topical nutraceutical-peptide combinations

Hair shedding blamed on stress often fits telogen effluvium, but it frequently overlaps with androgenetic alopecia, alopecia areata, systemic illness, weight change, or medication effects. New data on a topical EGCG-biotin-Pal-GHK combination support a mechanistic scalp TGF-β/BMP hypothesis, but they do not replace careful diagnosis or treatments supported by stronger clinical evidence [1-8].

September 16, 2026

Scientific Article: Modulation of the follicular microenvironment as an emerging preclinical therapy for pattern hair loss

New

Scientific News

Scientific Article: Modulation of the follicular microenvironment as an emerging preclinical therapy for pattern hair loss

Follicular microenvironment modulation is emerging as a promising experimental strategy for pattern hair loss, but in 2026 the evidence base remains predominantly preclinical. New mouse, biomaterials, and TGF-β/BMP signaling studies strengthen the biological rationale, while real-world clinical management still depends on therapies supported by more direct human data.

September 16, 2026