Longevity & lifestyle medicine

Longevity

Living longer and better: the science of healthy ageing.

20 resources

Patient guides

Everything about skin ageing: why we age and how to keep healthy skin for longer

Skin ageing is a natural process influenced by genetics and, above all, by external factors such as the sun, tobacco and lifestyle. Prevention, photoprotection, healthy habits and aesthetic medicine based on biostimulation make it possible to keep healthy, natural and younger-looking skin for longer.

July 23, 2026

Physical exercise and skin health: a natural treatment to age better

Regular physical activity favours skin health by improving circulation, decreasing inflammation and enhancing the natural repair mechanisms. Combined with good sleep, a balanced diet and photoprotection, it constitutes one of the pillars of healthy ageing.

July 23, 2026

Sleep and skin health: regeneration begins while we sleep

Sleep is one of the main natural repair mechanisms of the organism. Sleeping between seven and nine quality hours favours skin regeneration, collagen synthesis, immune balance and healthy ageing, while the lack of rest accelerates the deterioration of the skin.

July 23, 2026

Alcohol and skin health: how it affects skin ageing

Excessive alcohol consumption favours skin ageing through dehydration, inflammation and oxidative stress. It can also worsen rosacea, delay healing and alter the quality of the skin. Reducing consumption is part of a healthy lifestyle and of a healthy ageing strategy.

July 23, 2026

How to age with healthy skin

Ageing with healthy skin is possible through healthy habits, daily photoprotection, a balanced diet, exercise and medical treatments aimed at stimulating the natural mechanisms of repair. The goal is not to change the face, but to preserve healthy skin and a natural appearance.

July 23, 2026

Scientific news

Anti-obesity treatments: the most effective have the most side effects

A meta-analysis of more than 200 studies, published in the BMJ and reported by Sciences et Avenir/AFP, shows that the most effective GLP-1 anti-obesity treatments are also those that cause the most adverse effects. Tirzepatide (Mounjaro) and CagriSema allow weight loss of around 15%, versus ~10% for semaglutide alone (Wegovy). Semaglutide and tirzepatide reduce cardiovascular risks. None has demonstrated an overall improvement in quality of life; the hindsight remains limited. A major challenge for health authorities (recent reimbursement of Wegovy and Mounjaro in France, under strict criteria).

July 31, 2026

Running: why insufficient sleep could increase the risk of injury

A 2025 study (Applied Sciences) profiled the sleep of 425 recreational runners and identified four profiles. The "poor sleepers" (short sleep + poor quality + disturbances, ~37%) had an injury probability close to 68%, well above regular sleepers. Observational, cross-sectional study: it shows an association, not causation. Sleep affects muscle recovery, alertness, perception of effort and pain. It remains one factor among others (load, energy, strength, technique). Key message: when sleep deteriorates durably, the body tolerates load less well.

July 31, 2026

Losing weight after 40: why is it harder and which strategies really work?

After the age of 40, losing weight often becomes harder: loss of muscle mass (sarcopenia), hormonal changes (menopause, declining testosterone), disrupted sleep and chronic stress alter the energy balance. Basal metabolism falls only slightly before 60. Effective strategies rely on adequate protein intake (1.2–1.6 g/kg/day), strength training (2–3 sessions/week), at least 150 min of moderate activity, sleep optimisation and management of medical factors. Sources: EASO, ESPEN, Endocrine Society, ACSM.

July 31, 2026

The hallmarks of aging: 2023 update

Analysis of the updated 'hallmarks of aging' and their implications for longevity medicine.

July 20, 2026

Why do some centenarians age differently? What their metabolism reveals

Centenarians display a particular metabolic signature: better-regulated inflammation, more efficient energy metabolism and better-preserved steroid hormones. An observational study of more than 5,000 participants that sheds light on healthspan without proving causation.

July 8, 2026

Why is the gut microbiome so important for our health?

The gut microbiome, a genuine functional organ, influences digestion, immunity, metabolism and inflammation. The best current evidence supports a varied, plant-rich, minimally processed diet far more than microbiome tests or ultra-personalised nutrition.

July 1, 2026

Apelin: the exercise hormone that could revolutionise the treatment of sarcopenia?

Apelin is an exerkine — a hormone produced by muscle during exercise — whose production declines with age. In animals, it stimulates satellite cells, improves mitochondrial function and metabolism, and restores muscle regeneration (Nature Medicine, 2018). No apelin-based treatment is available in clinical practice: analogues, APJ receptor agonists and microneedle patches (Pyr-Apelin-13) remain preclinical. The reference treatment for sarcopenia is still resistance exercise combined with adequate protein intake.

June 18, 2026

Omega-3: what are their real health benefits? What science really says

Omega-3s (ALA, EPA, DHA) are among the most studied nutrients. The evidence is solid for lowering triglycerides, targeted cardiovascular prevention with high-dose purified EPA (REDUCE-IT, −25%) and pregnancy (DHA), but nuanced for memory, Alzheimer's and many chronic diseases. Not all omega-3s are equal: oily fish, a standard supplement and a purified-EPA medicine do not have the same effects.

June 17, 2026

GLP-1 drugs and hair loss: a real side effect or a consequence of weight loss?

A large BMJ cohort study shows an increased risk of alopecia in patients treated with GLP-1 agonists (semaglutide, tirzepatide) compared with other antidiabetics (+37% vs SGLT-2, +68% vs DPP-4). The absolute risk remains low and the most likely mechanism is telogen effluvium related to rapid weight loss. The hair loss is generally reversible; stopping treatment is rarely necessary.

June 16, 2026